When GM crops and foods were first introduced in the late 1990s, some scientists raised concerns that genetic modification was imprecise and unpredictable and could result in harm to health and the environment. They warned that:

• GM could create foods that are toxic, allergenic and less nutritious than their non-GM counterparts

• GM crops could damage vulnerable wild plant and animal populations
• GM plants cannot be recalled, but as living organisms will propagate, transmitting any damaging properties from generation to generation
• GM crops could cause irreversible alterations to the food supply, with serious consequences for the environment and human and animal health.

A report by Testbiotech e.V. Institute for Independent Impact Assessment in Biotechnology
Authors: Christoph Then, Christof Potthof October 2009

Summary points compiled by GMWatch

GM food safety testing

• European Food Safety Authority's (EFSA) concept of risk assessment of genetically modified (GM) plants is essentially based upon guidelines that were developed by the OECD (Organisation for Economic Co-operation and Development) as early as 1993 on the assumption that the risks posed by GM plants are the same as those posed by conventional plants.

• But the differences between conventional breeding and genetic engineering of plants are becoming clearer in the light of current genome research. Experience gained from conventional breeding cannot be applied to GM plants.
• Changes in the activity of plant genes in the genetic engineering process are not an expression of natural gene regulation but an indication of disruption.